Title: Integration of Process Design and Control - Optimization Formulations and Challenges

The design of a plant can significantly affect its inherent ability to be satisfactorily controlled. A plant design which is optimal on the basis of steady-state considerations, but which has poor dynamic characteristics, may not be able to achieve the expected economic performance in practice and may moreover fail to satisfy operational, safety and environmental constraints. It has therefore become increasingly important for dynamic performance to be considered during the design phase rather than as a post-design exercise when design changes become increasingly difficult and often prohibitively costly to implement. Optimization-based formulations for addressing various forms of this problem will be presented, solution strategies discussed and some key challenges identified.